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Extinct dire wolves brought back to life in incredible world-first

By T.K. Randall
April 8, 2025 · Comment icon 58 comments
Dire wolf pups
The first living dire wolves in 10,000 years. Image Credit: Colossal Biosciences / Twitter
Scientists have announced that they have successfully brought an animal back from extinction for the first time.
In news that seems to have come out of nowhere, Texas-based firm Colossal Biosciences has revealed that it has succeeded in bringing dire wolves back from extinction, making this the first time that any extinct species has been resurrected using modern 'de-extinction' techniques.

In a video, the firm introduced the world to Romulus and Remus - two dire wolf pups - while celebrating the fact that this was the first time anyone had heard a dire wolf howl in 10,000 years.

Made famous by Game of Thrones, dire wolves were a particularly large species of wolf, (though they never grew to the size of the wolves seen in the show).

To bring them back to life, scientists used cloning and gene-editing techniques.

"This massive milestone is the first of many coming examples demonstrating that our end-to-end de-extinction technology stack works," said Colossal's chief executive Ben Lamm.

"Our team took DNA from a 13,000 year old tooth and a 72,000 year old skull and made healthy dire wolf puppies."
"It was once said, 'any sufficiently advanced technology is indistinguishable from magic'. Today, our team gets to unveil some of the magic they are working on and its broader impact on conservation."

The big question is - what's next ?

If it is possible to bring dire wolves back from the dead, it should also be possible to resurrect woolly mammoths, thylacines, saber-toothed tigers and more besides.

While bringing back the dinosaurs is still beyond the abilities of science, creating a park filled with resurrected prehistoric mammal species could now be a very real possibility.

You can check out the video of the dire wolf pups for yourself below.



Source: Independent | Comments (58)




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Recent comments on this story
Comment icon #49 Posted by Grim Reaper 6 5 days ago
That’s funny, it sounds like your thanksgiving dinner may eat you!
Comment icon #50 Posted by Piney 5 days ago
Exactly and it's 50-50 if you get a good or bad one.
Comment icon #51 Posted by iAlrakis 5 days ago
totally agree.  but certainly not dangerous like some people claim because their little pony got attacked. 
Comment icon #52 Posted by Grim Reaper 6 5 days ago
Rex was bought from a breeder, his mother was a full blooded Timberwolf and Dad was a full blooded German Shepherd. However, he didn’t look like a dog, he looked like a Wolf. He, ended up being the best and smartest Dog I have ever met and he was never vicious, the only thing that scared people was his size (weight approximately 100 lb+) and the way he looked. 
Comment icon #53 Posted by diablo_04 4 days ago
I don't  know why you are unable to realize that your anecdotal experience does not reflect the reality. End of the day a "wolfdogs" are dangerous animals to be around humans. They can and the are dangerous to other pets and kids, and you can try and justify it as much as you can but no one needs to have such breeds roaming around humans, and with a good reason they are forbidden in lot of places. Also its most likely you had a 3-4th generation of a wolfdog not a direct pup from a crossbreeding between Timberwolf and a German  Shepherd as they are forbidden in most countries. 
Comment icon #54 Posted by Grim Reaper 6 4 days ago
What personal experience do you have with Wolf Dogs? No, that’s not correct Rex was first generation breed from a full blooded female Timberwolf and a full blooded German Shepherd, there were 4 puppies and I picked Rex out of the litter myself. I also met mom and dad, this breeder was well known in Southern Missouri, however I can no longer remember his name this occurred in 1967 or 68 not sure anymore.  
Comment icon #55 Posted by flying squid 3 days ago
The genetic engineered dire wolves now can hunt the genetic engineered sheep Dolly.
Comment icon #56 Posted by Tatetopa 3 days ago
Dire wolves lived up to about 10k ago in an environment with large mammals like mammoths. Lots of fossils from La Brea tar pits. It was post glacial, no ice sheets. Having white fur on a grassy plain is not likely. DNA studies have put dire wolves in their own species, Aenocyon rather than Canus with grey wolves. They are related to African jackals as well and split off from a common ancestor a couple million years ago
Comment icon #57 Posted by MysteryMike 2 days ago
Lookalikes. They're just gray wolves that were genetically modified to resemble dire wolves. Regardless still an accomplish and one step further to de-extinction.
Comment icon #58 Posted by Amorlind 3 hours ago
Hello, Just to clear this : Canis Dirus and the actual gray wolf are not all all alike...2 different lineage since approximatively 5-6 millions years...what we see here is indeed a "simple" gene modification. The Canis Dirus wont come back.


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